Which of the following disorders is characterized by an abnormality in the fibrinogen molecule, leading to impaired fibrin clot formation?

A Afibrinogenemia
B Hypofibrinogenemia
C Dysfibrinogenemia ✓
D Hyperfibrinogenemia

Explanation

Dysfibrinogenemia is a rare bleeding disorder caused by mutations in the FGA, FGB, or FGG genes, leading to the production of abnormal fibrinogen molecules that cannot form proper fibrin clots.

Source

Orphanet Journal of Rare Diseases
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Hard MEDICAL Confidence: high