Which of the following proteins plays a crucial role in the regulation of fibrinolysis by binding to plasminogen and enhancing its conversion to plasmin?

A Tissue plasminogen activator (tPA) ✓
B Urokinase-type plasminogen activator (uPA)
C Plasminogen activator inhibitor-1 (PAI-1)
D Fibronectin

Explanation

Tissue plasminogen activator (tPA) binds to plasminogen and enhances its conversion to plasmin, which is the primary enzyme responsible for fibrinolysis.

Source

Hematology: Clinical Principles and Applications
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Hard MEDICAL Confidence: high