A patient with a rare coagulation disorder is found to have a mutation in the gene encoding for the enzyme responsible for converting factor X to its active form. Which coagulation factor is likely deficient in this patient?

A Factor VII ✓
B Factor IX
C Factor X
D Factor XI

Explanation

The conversion of factor X to its active form involves the action of factor VIIa as part of the tissue factor pathway. A deficiency in factor VII would lead to impaired activation of factor X.

Source

Williams Hematology
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Hard MEDICAL Confidence: medium