A patient with hemophilia A is given desmopressin to manage their condition. What is the mechanism of action of desmopressin in this context?

A It increases the production of factor VIII by stimulating the release of von Willebrand factor ✓
B It decreases the production of factor VIII by inhibiting the release of von Willebrand factor
C It increases the production of factor IX by stimulating the release of tissue factor
D It decreases the production of factor IX by inhibiting the release of tissue factor

Explanation

Desmopressin stimulates the release of von Willebrand factor, which in turn increases the production of factor VIII, thereby helping to manage hemophilia A.

Mnemonic

DDAVP = Desmopressin Decreases Attacks Via Production

Source

Williams Hematology
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Hard MEDICAL Confidence: high