Which coagulation disorder is caused by a deficiency of the enzyme ADAMTS13, leading to the formation of ultra-large von Willebrand factor multimers?

A Thrombotic thrombocytopenic purpura (TTP) ✓
B Hemolytic uremic syndrome (HUS)
C Disseminated intravascular coagulation (DIC)
D Immune thrombocytopenic purpura (ITP)

Explanation

Thrombotic thrombocytopenic purpura (TTP) is a coagulation disorder caused by a deficiency of the enzyme ADAMTS13, leading to the formation of ultra-large von Willebrand factor multimers.

Source

New England Journal of Medicine
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Hard MEDICAL Confidence: high