What is the primary function of von Willebrand factor in hemostasis?

A To activate factor X
B To bind and stabilize factor VIII ✓
C To inhibit platelet aggregation
D To promote fibrinolysis

Explanation

Von Willebrand factor plays a crucial role in hemostasis by binding and stabilizing factor VIII, which is essential for the intrinsic pathway of coagulation.

Mnemonic

VWF = Very Wonderful Factor

Source

Robbins and Cotran Pathologic Basis of Disease
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Medium MEDICAL Confidence: high