What is the name of the genetic disorder characterized by a deficiency of the von Willebrand factor-cleaving protease, ADAMTS13?

A Thrombotic thrombocytopenic purpura ✓
B Hemolytic uremic syndrome
C Disseminated intravascular coagulation
D Von Willebrand disease

Explanation

Thrombotic thrombocytopenic purpura is a genetic disorder characterized by a deficiency of the von Willebrand factor-cleaving protease, ADAMTS13, leading to excessive von Willebrand factor activity and thrombosis.

Source

New England Journal of Medicine, 2019
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Medium MEDICAL Confidence: high