A patient with a history of recurrent venous thromboembolism is found to have a mutation in the gene encoding which protein?

A Protein S
B Protein C
C Antithrombin III
D Factor V Leiden ✓

Explanation

Factor V Leiden is a mutation in the gene encoding factor V, which makes it resistant to inactivation by activated protein C. This leads to an increased risk of venous thromboembolism.

Source

Hematology textbooks
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Medium MEDICAL Confidence: high