Which of the following coagulation factors is synthesized by the endothelium and plays a crucial role in the regulation of coagulation and inflammation?

A Factor VIII
B Factor IX
C Tissue factor pathway inhibitor
D Thrombomodulin ✓

Explanation

Thrombomodulin is a coagulation factor synthesized by the endothelium that plays a crucial role in the regulation of coagulation and inflammation by binding to thrombin and activating protein C.

Source

Williams Hematology
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Medium MEDICAL Confidence: high