A patient with a coagulation disorder presents with a prolonged prothrombin time and activated partial thromboplastin time. Which of the following is the most likely diagnosis?

A Disseminated intravascular coagulation (DIC)
B Liver disease
C Vitamin K deficiency
D All of the above ✓

Explanation

Prolonged prothrombin time and activated partial thromboplastin time can be seen in various coagulation disorders, including DIC, liver disease, and vitamin K deficiency, which all affect the production or function of multiple coagulation factors.

Source

Harrison's Principles of Internal Medicine
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Hard MEDICAL Confidence: high