Which of the following coagulation factors is involved in the activation of factor XI, and its deficiency can lead to a bleeding disorder?

A Factor XII ✓
B Factor IX
C Factor VIII
D Prekallikrein

Explanation

Factor XII, also known as Hageman factor, is involved in the activation of factor XI, which is a crucial step in the intrinsic pathway of coagulation. A deficiency of factor XII can lead to a bleeding disorder.

Source

Hematology textbooks
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Medium MEDICAL Confidence: high