Which of the following statements is true regarding the role of endothelial cells in hemostasis?

A They produce only pro-coagulant factors
B They produce only anti-coagulant factors
C They produce both pro-coagulant and anti-coagulant factors ✓
D They do not play a role in hemostasis

Explanation

Endothelial cells play a crucial role in hemostasis by producing both pro-coagulant factors, such as tissue factor, and anti-coagulant factors, such as heparan sulfate and thrombomodulin.

Mnemonic

Endo-thelial = End on the wall, regulating coagulation

Source

Robbins and Cotran Pathologic Basis of Disease
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Easy MEDICAL Confidence: high