A patient with a deficiency of protein C is at increased risk of developing which of the following conditions?

A Deep vein thrombosis ✓
B Pulmonary embolism
C Bleeding disorders
D Sickle cell disease

Explanation

Protein C is an anticoagulant protein that inhibits the activity of factors V and VIII. A deficiency of protein C can lead to an increased risk of developing deep vein thrombosis due to the unregulated activation of coagulation factors.

Mnemonic

PC = Prevents Clots

Source

Harrison's Principles of Internal Medicine
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Hard MEDICAL Confidence: high