Which of the following coagulation disorders is associated with an increased risk of thrombosis due to a mutation in the protein C inhibitor, resulting in decreased protein C activity?

A Protein S deficiency
B Antithrombin III deficiency
C Protein C deficiency ✓
D Factor V Leiden mutation

Explanation

Protein C deficiency is a coagulation disorder that increases the risk of thrombosis due to decreased protein C activity, which normally inhibits factors Va and VIIIa.

Source

Hematology: Clinical Principles and Applications, 4th edition
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Medium MEDICAL Confidence: medium