What is the primary cause of thrombocytopenia in patients with thrombotic thrombocytopenic purpura?

A Autoantibody-mediated platelet destruction

B Platelet consumption due to microvascular thrombi formation ✓

C Bone marrow failure

D Spleen sequestration

Explanation

Thrombotic thrombocytopenic purpura is characterized by the formation of microvascular thrombi, which consumes platelets and leads to thrombocytopenia.

Source

Harrison's Principles of Internal Medicine

Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Medium MEDICAL Confidence: high

Language Translate

Flash News

Hepatitis C – Sign & Symptoms, Transmission, Risk factors, Diagnosis, Complication, Treatment and Prevention

Tuberculosis (TB) – Sign and Symptoms, Risk Factors, Diagnosis, Complications, Treatment and Prevention

Dengue Fever – Sign and Symptoms, Risk Factors, Diagnosis, Complications, Treatment and Prevention

Acute Myeloid Leukemia (AML) – Sign and Symptoms, Risk Factors, Diagnosis, Complications, Treatment and Prevention

Heart Attack (Myocardial Infarction) – Sign and Symptoms, Risk Factors, Diagnosis, Complications, Treatment and Prevention

Coronary Artery Disease (CAD) – Sign and Symptoms, Risk Factors, Diagnosis, Complications, Treatment and Prevention

Preservation of Urine Specimens – Principles, Methods and Clinical Significance

Chronic Myeloid Leukemia (CML) – Sign and Symptoms, Risk Factors, Diagnosis, Complications, Treatment and Prevention

Chronic Lymphocytic Leukemia (CLL) – Sign and Symptoms, Risk Factors, Diagnosis, Complications, Treatment and Prevention

Atrial Fibrillation (AFib) – Sign and Symptoms, Risk Factors, Diagnosis, Complications, Treatment and Prevention

Acute Respiratory Distress Syndrome (ARDS) – Sign and Symptoms, Risk factors, Diagnosis, Complications, Treatment and Prevention

Normal Values of Immunology Parameters

What is the primary cause of thrombocytopenia in patients with thrombotic thrombocytopenic purpura?

Explanation

Source

Subscribe to MedicoInfo