What is the role of Protein C in the coagulation pathway?

A To activate Factor X
B To inhibit the activation of Factor V and Factor VIII ✓
C To enhance the activation of Factor XII
D To degrade fibrinogen

Explanation

Protein C is a vitamin K-dependent serine protease that plays a critical role in regulating anticoagulation by inhibiting the activation of Factors V and VIII.

Source

Guyton and Hall Textbook of Medical Physiology
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Medium MEDICAL Confidence: high