Which of the following types of anemia is characterized by an abnormal hemoglobin structure?

A Iron-deficiency anemia
B Vitamin B12 deficiency anemia
C Sickle cell anemia ✓
D Pernicious anemia

Explanation

Sickle cell anemia is caused by a mutation in the HBB gene, leading to an abnormal hemoglobin structure.

Source

American Society of Hematology
Hematology Hematology: Anemia Hematology: Anemia Easy MEDICAL Confidence: high