A patient with anemia is found to have a low level of haptoglobin and an elevated level of lactate dehydrogenase (LDH). What is the most likely diagnosis?

A Autoimmune hemolytic anemia ✓
B Hereditary spherocytosis
C Hemolytic uremic syndrome
D Microangiopathic hemolytic anemia

Explanation

The combination of low haptoglobin and elevated LDH is indicative of intravascular hemolysis. Autoimmune hemolytic anemia is a condition where the immune system produces antibodies against the patient's own red blood cells, leading to their destruction.

Source

American Journal of Hematology
Hematology Hematology: Anemia Hematology: Anemia Medium MEDICAL Confidence: high