Which of the following is a characteristic of cold agglutinin disease?

A Autoantibodies that react with red blood cells at temperatures above 37°C
B Autoantibodies that react with red blood cells at temperatures below 37°C ✓
C Alloantibodies that react with platelets at any temperature
D Heterophile antibodies that react with leukocytes

Explanation

Cold agglutinin disease is characterized by autoantibodies that are active at temperatures below 37°C, leading to hemolysis, making option B the correct answer.

Source

Hematology textbook by Williams
Hematology Hematology: Blood Components Hematology: Blood Components Medium MEDICAL Confidence: high