Which of the following anemias is characterized by the accumulation of denatured hemoglobin, resulting in the formation of Heinz bodies?

A Glucose-6-phosphate dehydrogenase deficiency anemia ✓
B Sickle cell anemia
C Thalassemia major
D Hereditary spherocytosis

Explanation

Glucose-6-phosphate dehydrogenase deficiency anemia is characterized by the accumulation of denatured hemoglobin, resulting in the formation of Heinz bodies, which are inclusions within red blood cells composed of denatured hemoglobin.

Source

Wintrobe's Clinical Hematology
Hematology Hematology: Anemia Hematology: Anemia Hard MEDICAL Confidence: high