Which of the following stages of hematopoiesis is characterized by the expression of the CD34 antigen and the loss of self-renewal capacity?

A Hematopoietic stem cell stage
B Multipotent progenitor stage ✓
C Oligopotent progenitor stage
D Unipotent progenitor stage

Explanation

The multipotent progenitor stage is characterized by the expression of the CD34 antigen and the loss of self-renewal capacity, marking a transition from a self-renewing hematopoietic stem cell to a more differentiated progenitor cell.

Source

- Orkin & Zon (2008) - Hematopoiesis: an evolving paradigm for stem cell biology
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Hard MEDICAL Confidence: high