Which of the following cellular mechanisms is responsible for the asymmetric cell division of hematopoietic stem cells?

A Mitotic spindle orientation ✓
B Cytokinesis
C Apoptosis
D Autophagy

Explanation

Asymmetric cell division is a critical mechanism that allows hematopoietic stem cells to maintain their population while generating differentiated progeny. Mitotic spindle orientation is the key cellular mechanism that regulates asymmetric cell division, ensuring that one daughter cell retains stem cell properties while the other daughter cell differentiates.

Source

Cell Stem Cell
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Medium MEDICAL Confidence: high