What is the significance of Notch signaling in hematopoiesis?

A It promotes the differentiation of hematopoietic stem cells into myeloid lineage
B It inhibits the self-renewal of hematopoietic stem cells
C It regulates the balance between myeloid and lymphoid lineage commitment ✓
D It has no role in hematopoiesis

Explanation

Notch signaling plays a crucial role in regulating the balance between myeloid and lymphoid lineage commitment, ensuring proper hematopoiesis.

Source

Molecular Biology of the Cell, Alberts et al.
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Medium MEDICAL Confidence: high