Which of the following growth factors is involved in the regulation of thrombopoiesis, particularly in the maturation of megakaryocytes?

A Erythropoietin (EPO)
B Granulocyte-colony stimulating factor (G-CSF)
C Thrombopoietin (TPO) ✓
D Stem cell factor (SCF)

Explanation

Thrombopoietin (TPO) is a growth factor that plays a critical role in the regulation of thrombopoiesis, promoting the proliferation, differentiation, and maturation of megakaryocytes.

Source

Lodish et al. (2000) - Molecular Cell Biology
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Easy MEDICAL Confidence: high