What is the primary function of the glycoprotein, CD34, in hematopoiesis?
A
To promote cell adhesion and homing of hematopoietic stem cells
✓
B
To regulate the proliferation and differentiation of hematopoietic progenitor cells
C
To inhibit the apoptosis of mature blood cells
D
To facilitate the egress of mature blood cells from the bone marrow
Explanation
CD34 is a transmembrane phosphoglycoprotein that plays a crucial role in the adhesion and homing of hematopoietic stem cells to the bone marrow niche.
Source
Alberts et al. (2002) - Molecular Biology of the Cell
Hematology
Hematology: Hematopoiesis
Hematology: Hematopoiesis
Medium
MEDICAL
Confidence: high
