Which of the following molecules plays a crucial role in the adhesion of hematopoietic stem cells to the bone marrow stroma?

A CXCL12

B SCF

C VCAM-1 ✓

D CD34

Explanation

VCAM-1 (Vascular Cell Adhesion Molecule-1) is an adhesion molecule expressed on the surface of bone marrow stromal cells that interacts with VLA-4 on hematopoietic stem cells, mediating their adhesion to the stroma.

Source

Lopez et al. Blood Cells, Molecules, and Diseases

Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Hard MEDICAL Confidence: medium

Language Translate

Flash News

Hepatitis C – Sign & Symptoms, Transmission, Risk factors, Diagnosis, Complication, Treatment and Prevention

Tuberculosis (TB) – Sign and Symptoms, Risk Factors, Diagnosis, Complications, Treatment and Prevention

Dengue Fever – Sign and Symptoms, Risk Factors, Diagnosis, Complications, Treatment and Prevention

Acute Myeloid Leukemia (AML) – Sign and Symptoms, Risk Factors, Diagnosis, Complications, Treatment and Prevention

Heart Attack (Myocardial Infarction) – Sign and Symptoms, Risk Factors, Diagnosis, Complications, Treatment and Prevention

Coronary Artery Disease (CAD) – Sign and Symptoms, Risk Factors, Diagnosis, Complications, Treatment and Prevention

Preservation of Urine Specimens – Principles, Methods and Clinical Significance

Chronic Myeloid Leukemia (CML) – Sign and Symptoms, Risk Factors, Diagnosis, Complications, Treatment and Prevention

Chronic Lymphocytic Leukemia (CLL) – Sign and Symptoms, Risk Factors, Diagnosis, Complications, Treatment and Prevention

Atrial Fibrillation (AFib) – Sign and Symptoms, Risk Factors, Diagnosis, Complications, Treatment and Prevention

Acute Respiratory Distress Syndrome (ARDS) – Sign and Symptoms, Risk factors, Diagnosis, Complications, Treatment and Prevention

Normal Values of Immunology Parameters

Which of the following molecules plays a crucial role in the adhesion of hematopoietic stem cells to the bone marrow stroma?

Explanation

Source

Subscribe to MedicoInfo