Which of the following is a consequence of defective asymmetric cell division in hematopoietic stem cells?

A Increased production of red blood cells
B Decreased production of white blood cells
C Impaired self-renewal and differentiation of hematopoietic stem cells ✓
D Enhanced production of platelets

Explanation

Asymmetric cell division is crucial for maintaining the balance between self-renewal and differentiation of hematopoietic stem cells. Defects in this process can lead to impaired self-renewal and differentiation, affecting blood cell production.

Source

Nature Reviews Immunology
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Hard MEDICAL Confidence: medium