Which of the following proteins is involved in the adhesion of hematopoietic stem cells to the bone marrow niche?

A VLA-4 ✓

B VLA-5

C CD31

D CD44

Explanation

VLA-4 (Very Late Antigen-4) is an integrin that plays a crucial role in the adhesion of hematopoietic stem cells to the bone marrow niche, facilitating their interaction with stromal cells and extracellular matrix.

Source

Lodish et al. Molecular Cell Biology

Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Hard MEDICAL Confidence: high

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Which of the following proteins is involved in the adhesion of hematopoietic stem cells to the bone marrow niche?

Explanation

Source

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