What is the role of the hedgehog signaling pathway in the regulation of hematopoietic stem cell self-renewal and differentiation?

A It promotes the self-renewal of HSCs ✓
B It inhibits the differentiation of HSCs
C It has no effect on HSCs
D It regulates the quiescence of HSCs

Explanation

The hedgehog signaling pathway plays a crucial role in regulating the self-renewal and differentiation of hematopoietic stem cells.

Source

Scientific literature
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Hard MEDICAL Confidence: high