What is the function of the stromal cell-derived factor 1 (SDF-1) in hematopoiesis?
A
To promote the differentiation of hematopoietic stem cells into erythrocytes
B
To regulate the migration and homing of hematopoietic stem cells to the bone marrow
✓
C
To inhibit the proliferation of hematopoietic stem cells
D
To induce the apoptosis of hematopoietic stem cells
Explanation
SDF-1, also known as CXCL12, plays a crucial role in the migration and homing of hematopoietic stem cells to the bone marrow, where they can undergo differentiation and proliferation.
Hematology
Hematology: Hematopoiesis
Hematology: Hematopoiesis
Medium
MEDICAL
Confidence: high