Which of the following metabolic pathways is essential for the maintenance of hematopoietic stem cell quiescence?

A Glycolysis
B Pentose phosphate pathway ✓
C Fatty acid oxidation
D Amino acid metabolism

Explanation

The pentose phosphate pathway is essential for the maintenance of hematopoietic stem cell quiescence by providing a source of NADPH and ribose-5-phosphate, which are necessary for the synthesis of nucleotides and the regulation of oxidative stress.

Source

Recent research articles on hematopoiesis
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Hard MEDICAL Confidence: medium