Which of the following transcription factors plays a crucial role in the development and maintenance of hematopoietic stem cells in the fetal liver?

A GATA1
B GATA2 ✓
C SCL
D RUNX1

Explanation

GATA2 is a transcription factor that is essential for the development and maintenance of hematopoietic stem cells in the fetal liver, and plays a critical role in regulating the expression of genes involved in hematopoiesis.

Source

Orkin et al. (2008) Nature Reviews Immunology
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Hard MEDICAL Confidence: medium