How does the concentration of 2,3-bisphosphoglycerate (2,3-BPG) affect the oxygen-binding properties of hemoglobin?
A
2,3-BPG increases the affinity of hemoglobin for oxygen
B
2,3-BPG decreases the affinity of hemoglobin for oxygen
✓
C
2,3-BPG has no effect on the oxygen-binding properties of hemoglobin
D
2,3-BPG increases the affinity of hemoglobin for carbon dioxide
Explanation
2,3-BPG binds to deoxyhemoglobin and decreases its affinity for oxygen, allowing for more efficient release of oxygen to tissues.
Source
Berne and Levy Physiology
Hematology
Hematology: Hemoglobin and Oxygen Transport
Hematology: Hemoglobin and Oxygen Transport
Hard
MEDICAL
Confidence: high
