How does the concentration of 2,3-bisphosphoglycerate (2,3-BPG) affect the oxygen-binding affinity of hemoglobin?
A
It increases the oxygen-binding affinity of hemoglobin
B
It decreases the oxygen-binding affinity of hemoglobin
✓
C
It has no effect on the oxygen-binding affinity of hemoglobin
D
It increases the cooperativity of oxygen binding to hemoglobin
Explanation
2,3-Bisphosphoglycerate (2,3-BPG) decreases the oxygen-binding affinity of hemoglobin, allowing for more efficient release of oxygen to tissues.
Source
Physiology textbooks
Hematology
Hematology: Hemoglobin and Oxygen Transport
Hematology: Hemoglobin and Oxygen Transport
Easy
MEDICAL
Confidence: high
