What is the significance of the hemoglobin-haptoglobin complex in the prevention of kidney damage?

A It prevents the loss of iron from the body
B It reduces the risk of kidney stone formation
C It prevents the filtration of hemoglobin through the glomeruli ✓
D It enhances the production of erythropoietin

Explanation

The hemoglobin-haptoglobin complex plays a crucial role in preventing kidney damage by preventing the filtration of free hemoglobin through the glomeruli, which can cause oxidative damage and inflammation.

Source

Guyton and Hall Textbook of Medical Physiology
Hematology Hematology: Hemoglobin and Oxygen Transport Hematology: Hemoglobin and Oxygen Transport Medium MEDICAL Confidence: high