How does nitric oxide affect the oxygen-binding properties of hemoglobin?

A It increases the affinity of hemoglobin for oxygen
B It decreases the affinity of hemoglobin for oxygen ✓
C It has no effect on the oxygen-binding properties of hemoglobin
D It binds to hemoglobin and reduces its ability to transport oxygen

Explanation

Nitric oxide binds to hemoglobin and reduces its affinity for oxygen, allowing for more efficient release of oxygen to tissues.

Source

Journal of Biological Chemistry
Hematology Hematology: Hemoglobin and Oxygen Transport Hematology: Hemoglobin and Oxygen Transport Hard MEDICAL Confidence: medium