What is the term for the abnormal hemoglobin variant characterized by a point mutation in the beta-globin gene, leading to a reduced affinity for oxygen?

A Hemoglobin C
B Hemoglobin E
C Hemoglobin Kansas ✓
D Hemoglobin Yoshida

Explanation

Hemoglobin Kansas is an abnormal hemoglobin variant with a reduced affinity for oxygen due to a point mutation in the beta-globin gene.

Source

Orphanet Journal of Rare Diseases
Hematology Hematology: Hemoglobin and Oxygen Transport Hematology: Hemoglobin and Oxygen Transport Hard MEDICAL Confidence: medium