What is the significance of the Bohr effect in hemoglobin and oxygen transport?

A It describes the increase in oxygen binding affinity with increasing pH
B It explains the decrease in oxygen binding affinity with increasing carbon dioxide levels ✓
C It describes the cooperative binding of oxygen to hemoglobin
D It explains the role of 2,3-Bisphosphoglycerate in oxygen binding

Explanation

The Bohr effect refers to the decrease in oxygen binding affinity of hemoglobin with increasing carbon dioxide levels and decreasing pH, which facilitates oxygen release to tissues.

Source

Guyton and Hall Textbook of Medical Physiology
Hematology Hematology: Hemoglobin and Oxygen Transport Hematology: Hemoglobin and Oxygen Transport Medium MEDICAL Confidence: high