What is the effect of an increase in temperature on the oxygen-binding affinity of hemoglobin?

A Increase in affinity
B Decrease in affinity ✓
C No effect on affinity
D Binds oxygen more loosely

Explanation

An increase in temperature decreases the oxygen-binding affinity of hemoglobin, allowing for more oxygen to be released to tissues.

Source

Guyton and Hall Textbook of Medical Physiology
Hematology Hematology: Hemoglobin and Oxygen Transport Hematology: Hemoglobin and Oxygen Transport Medium MEDICAL Confidence: high