Which blood component is responsible for the scavenging of haptoglobin-hemoglobin complexes from the circulation?

A CD163-expressing monocytes and macrophages ✓
B Hepatocytes via receptor-mediated endocytosis
C Kupffer cells in the liver through phagocytosis
D Neutrophils through the release of granular enzymes

Explanation

CD163 is a receptor expressed on monocytes and macrophages that binds haptoglobin-hemoglobin complexes, facilitating their removal from the circulation and preventing oxidative damage and inflammation.

Source

Blood Journal, American Society of Hematology
Hematology Hematology: Blood Components Hematology: Blood Components Hard MEDICAL Confidence: high