What is the primary function of the pentose phosphate pathway in red blood cells?

A To generate ATP for energy production
B To produce NADPH for antioxidant defense ✓
C To synthesize cholesterol for membrane maintenance
D To break down glucose for glycolysis

Explanation

The pentose phosphate pathway in red blood cells is primarily responsible for generating NADPH, which is used to maintain the levels of reduced glutathione and protect against oxidative damage.

Source

Guyton and Hall Textbook of Medical Physiology
Hematology Hematology: Blood Components Hematology: Blood Components Medium MEDICAL Confidence: high