What is the primary mechanism by which neutrophils undergo apoptosis, or programmed cell death, in the context of hematopoiesis?

A Activation of caspase-3 ✓
B Inhibition of NF-κB
C Downregulation of Bcl-2
D Upregulation of TNF-α

Explanation

Neutrophils undergo apoptosis through a mechanism involving the activation of caspase-3, which is a key enzyme in the apoptotic pathway.

Source

Blood journal
Hematology Hematology: Blood Components Hematology: Blood Components Hard MEDICAL Confidence: high