What is the role of CD4+ T cells in the regulation of B cell activation and antibody production?

A Activation of B cells through CD40 ligand interaction ✓
B Inhibition of B cell activation through cytokine suppression
C Neutral regulation, having no effect on B cell activation
D Enhancement of B cell activation through IL-4 production

Explanation

CD4+ T cells, also known as T helper cells, play a crucial role in the activation and regulation of B cells. They express CD40 ligand on their surface, which interacts with CD40 on B cells, leading to B cell activation and subsequent antibody production.

Source

Janeway's Immunobiology
Hematology Hematology: Blood Components Hematology: Blood Components Medium MEDICAL Confidence: high