Which blood component is responsible for the removal of senescent red blood cells from the circulation?

A Neutrophils
B Macrophages in the spleen ✓
C Lymphocytes
D Eosinophils

Explanation

Macrophages in the spleen recognize and remove senescent or damaged red blood cells from the circulation, helping to maintain the quality of the red blood cell population.

Source

Robbins and Cotran Pathologic Basis of Disease
Hematology Hematology: Blood Components Hematology: Blood Components Hard MEDICAL Confidence: high