What is the role of lysosomal enzymes in the pathogenesis of Gaucher's disease?

A Accumulation of glucocerebroside due to enzyme deficiency ✓
B Breakdown of glycogen to glucose
C Synthesis of cholesterol from acetyl-CoA
D Degradation of branched-chain amino acids

Explanation

Gaucher's disease is a lysosomal storage disorder caused by a deficiency of the enzyme glucocerebrosidase, leading to the accumulation of glucocerebroside.

Source

Harper's Biochemistry
Enzymes in Disease Biochemistry Lysosomal Storage Disorders Medium MEDICAL Confidence: high