What is the primary mechanism by which the body regulates protein synthesis in response to changes in dietary amino acid availability?

A Feedback inhibition of amino acid biosynthesis
B Allosteric activation of initiation factors
C mTOR-mediated signaling pathway ✓
D Transcriptional regulation of gene expression

Explanation

The mTOR (mechanistic target of rapamycin) pathway is a critical regulator of protein synthesis in response to changes in dietary amino acid availability, energy status, and growth factors.

Source

Alberts et al. (2002) Molecular Biology of the Cell
Protein Metabolism Biochemistry Regulation of Protein Synthesis Hard MEDICAL Confidence: high