Which of the following hormones is involved in the regulation of bone mineral density and calcium homeostasis through its effects on osteoclasts and osteoblasts?

A Parathyroid hormone (PTH) ✓
B Calcitonin
C Insulin-like growth factor-1 (IGF-1)
D Growth hormone

Explanation

PTH plays a crucial role in maintaining calcium homeostasis by stimulating osteoclast activity, which leads to bone resorption and increased calcium release into the bloodstream.

Source

Harrison's Principles of Internal Medicine
Hormones and Endocrine Markers Endocrinology Bone and Mineral Metabolism Hard MEDICAL Confidence: high