What is the name of the enzyme deficiency that leads to the accumulation of glycosaminoglycans in lysosomes, resulting in Hurler syndrome?

A Alpha-L-iduronidase ✓
B Beta-glucuronidase
C Alpha-galactosidase
D Beta-hexosaminidase

Explanation

Alpha-L-iduronidase is the enzyme responsible for breaking down glycosaminoglycans, and its deficiency leads to the accumulation of these molecules in lysosomes, resulting in Hurler syndrome.

Source

Biochemistry textbooks
Enzymes in Disease Biochemistry Lysosomal Storage Diseases Hard MEDICAL Confidence: high