Which of the following biochemical pathways is responsible for the generation of reducing equivalents in the form of NADH and FADH2 during the breakdown of fatty acids?

A Citric acid cycle
B Glycolysis
C Pentose phosphate pathway
D Beta-oxidation ✓

Explanation

Beta-oxidation is the process by which fatty acids are broken down to generate acetyl-CoA, NADH, and FADH2.

Mnemonic

Beta = Breakdown → fatty acids are broken down

Source

Nelson et al., Lehninger Principles of Biochemistry
Fundamentals of Biochemistry Metabolic Pathways Lipid Metabolism Hard MEDICAL Confidence: high