What is the primary function of the chloride shift in maintaining acid-base balance during carbon dioxide transport?

A To increase the pH of the blood
B To facilitate the transport of oxygen to tissues
C To maintain electroneutrality in red blood cells ✓
D To reduce the concentration of bicarbonate ions in plasma

Explanation

The chloride shift is a process that occurs in red blood cells, where chloride ions move into the cell and bicarbonate ions move out, helping to maintain electroneutrality and facilitate the transport of carbon dioxide.

Source

Guyton and Hall Textbook of Medical Physiology
Electrolytes and Acid-Base Balance Physiology Acid-Base Balance and Transport of Gases Medium MEDICAL Confidence: high